Could acetaminophen in pregnancy affect ADHD threat?

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Taking pain-relief medicine that comprise acetaminophen, akin to Tylenol, for a month or extra throughout pregnancy may double the danger of attention-deficit hyperactivity dysfunction (ADHD) in kids, a brand new examine suggests.

Nonetheless, short-term use of the drug in pregnancy may truly scale back ADHD threat, the identical examine indicated.

The brand new findings – which some scientists dispute – come from Norwegian analysis involving greater than 110,000 kids born between 1999 and 2009, and their dad and mom. Mothers in the examine stuffed out questionnaires throughout and after pregnancy reporting on medical circumstances and drugs use. Fathers answered questions on medicine use through the 6 months previous to their accomplice’s pregnancy.

Virtually half of the ladies used acetaminophen throughout pregnancy. Simply over 2,200 of the kids had been later identified with ADHD.

In response to the outcomes printed in the journal Pediatrics, kids born to girls who took acetaminophen for 29 days or extra throughout pregnancy both consecutively or unfold out over an extended interval had greater than double the danger of creating ADHD in comparison with youngsters born to mothers who didn’t use acetaminophen long-term. Dads who took the drug for lengthy intervals previous to conception additionally noticed double the danger of ADHD in their youngsters, the authors reported.


Alternatively, the ADHD threat for youngsters decreased barely when girls took acetaminophen for 7 days or much less throughout pregnancy, the examine stated. After greater than 7 days of use, the danger of ADHD in offspring started to rise, the researchers acknowledged.

The findings solely present an affiliation between long-term use of acetaminophen and ADHD, and don’t show that one factor causes the opposite. In truth, two scientists chatting with CNN referred to as the outcomes into query. They stated the examine depends on codes in the kids’s medical data that might embody issues apart from ADHD. It additionally bases the findings on dad and mom’ personal experiences of their acetaminophen use, which is probably not dependable, the consultants stated.

In an editorial accompanying the examine, Dr. Mark Wolraich stated the massive variety of individuals lends weight to the findings, however concluded that extra analysis is required. Many elements, together with genetics, can contribute to ADHD threat, he famous.

It’s frequent to take acetaminophen throughout pregnancy for ache reduction and fever discount, and the drug has lengthy been thought of secure. Nonetheless, it’s a good suggestion to seek the advice of together with your physician earlier than taking any drugs.

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